News of all that's transpired on and off the football field
In other ties, Serie A champions Juventus face Europa League winners Atletico Madrid and Barcelona take on Olympique Lyonnais.
All the latest football news from around Europe.
Defending champions Bayern Munich must face Diego Simeone's Atletico Madrid after they were drawn together in Champions League Group A alongside Salzburg and Lokomotiv Moscow.
While Lyon rallied to hold Leipzig 2-2 after a Memphis Depay strike, it was the English clubs who made a mark on the night. Liverpool and Chelsea moved into the last 16 with contrasting wins and now all four English clubs, including Manchester City and Tottenham Hotspur, are in the Champions League knockouts this season.
Schick on target again as Leverkusen win, Leipzig thrashed 5-1
The hosts could have snatched victory in the last action of the game but Michael Gregoritsch's point-blank header was saved by Lukas Hradecky.
Roundup of the matches being held across major football leagues in Europe
Barcelona thrashed Real Betis 5-1 on Wednesday to book their spot in the Copa del Rey quarter-finals.
Neuer made the squad despite playing in just one official game, a friendly against Austria on Friday, since breaking a bone in his foot in September but talented 22-year-old Sane was the biggest name to miss out.
Manchester United beat AC Milan 5-4 on penalties after their International Champions Cup match in Cardiff's Millennium Stadium ended 2-2 in regulation time on Saturday.
Barcelona were held to a 0-0 home draw by Galatasaray in the first leg of their Europa League last-16 tie
Bundesliga leaders Bayern Munich crushed Freiburg 4-0 on Saturday, recording their 13th successive Bundesliga victory and extending their league unbeaten streak to 46.
Hertha Berlin's Salomon Kalou scored twice, including a stoppage-time penalty, to earn a last-gasp 2-2 draw at Bundesliga leaders Borussia Dortmund on Saturday.
'There is no advantage. I always prefer to play in front of supporters even away from home because that's what football is all about, but that's the situation we face'
A summary of the opening day's action in the UEFA Champions league on Tuesday.
Galatasaray, fined 50,000 euros ($62,575) last month over crowd trouble at a Champions League game away to Arsenal, are facing further sanctions after disturbances at Borussia Dortmund on Tuesday, UEFA said on Thursday.
Manchester City squandered a three-goal lead to draw 3-3 with Feyenoord in the Champions League on Tuesday.
Seven-times champions AC Milan, knocked out of the Champions League by Barcelona in the last two seasons, were drawn against the Catalans again in the group stage of this season's competition on Friday.
Images from football matches played in Europe on Friday.
Robert Lewandowski struck twice to steer champions Bayern Munich to a 2-1 win at Hamburg SV on Friday that stretched their lead at the top to 11 points as the Bundesliga resumed following a one-month winter break.
Paulo Dybala came off the bench to give unbeaten Serie A leaders Juventus a 1-0 win away to a brave Bologna side who had the better of the match and hit the post in stoppage time on Sunday.
Images from the UEFA Champions League matches played on Tuesday night.
Manchester City made it five wins out of five in the Premier League and Cristiano Ronaldo scored five goals for Real Madrid but Chelsea and Juventus continued to struggle at the weekend as the Champions League looms.
News of all that's transpired on and off the football field
Kylian Mbappe scored twice in the second half to help his side to a 4-1 comeback win at 10-man Barcelona
Levante striker Roger Marti brushed off squandering a penalty to score the winning goal as his side pulled off a shock 2-1 La Liga victory at Real Madrid
A solid defence helped Schalke 04 secure a 1-0 win at home to Borussia Moenchengladbach on Friday that lifted them above their rivals into third spot in the Bundesliga in the battle for Champions League places.
Liverpool's Slot not nervous ahead of Anfield debut
Cristiano Ronaldo opened the scoring as Juventus beat visiting Bologna 2-1 on Saturday to move four points clear at the top of the Serie A table. Ronaldo struck from close range after 19 minutes, but Danilo levelled for the visitors soon afterwards.
A summary of Saturday's action in LaLiga, Ligue 1 and the Bundesliga.
IMAGES from the UEFA Champions League matches played on Wednesday
IMAGES from the Bundesliga matches played across Germany on Tuesday.
A summary of Tuesday's Champions League Round of 16, Second Leg, matches.
German fans have finally got their wish for a more exciting Bundesliga season and the title race will really hot up when leaders Bayern Munich lock horns with Borussia Dortmund on Saturday. Bayern's shock 2-1 defeat by Mainz 05 at the Allianz Arena in midweek means a home victory for second-placed Dortmund at the weekend would lift them within two points of the Bavarians with nine matches to go. Such is the worldwide interest in the top of the table clash, it will be broadcast to 208 countries. "Everyone wanted more suspense in the Bundesliga. Now you have it so all is well," Bayern coach Pep Guardiola told reporters. "We are not perfect. Sometimes you have to lose to understand what you need to do in order to become an even better team." Bayern, who are chasing a record fourth consecutive Bundesliga crown, had an 11-point lead earlier in the season. The defeat by Mainz and a 2-2 draw at Juventus in their Champions League last-16 first leg, after leading 2-0, have raised alarm bells among the supporters. "The results against Juve and Mainz were not good but our performances were," said Guardiola who is leaving at the end of the season to join Manchester City.
The 31-year-old is still recovering from the knee injury which forced him to limp out of the Euro 2016 final against France in the first half, coach Fernando Santos said.
Liverpool named former Borussia Dortmund coach Juergen Klopp as manager on Thursday with the club posting photos of him signing his contract on their official Twitter account.
Chelsea have topped the spending list with Manchester United not far behind, but West Ham United's business epitomises the TV riches which give all Premier League clubs spending power that only the elite teams in Spain or Germany can dream of.
Bayern Munich came from a goal down at home to beat Ingolstadt 3-1 on Saturday and make it three wins in three Bundesliga matches as they went two points clear at the top. The champions were far less convincing than in their Champions League 5-0 win over Rostov on Tuesday and were caught napping after eight minutes with Paraguayan Dario Lezcano slipping the ball through the legs of Manuel Neuer.
Germany expects 2.7 million people to attend matches in stadiums across the country and some 12 million in its fan zones for outdoor viewing, including on a long stretch of turf laid out in front of Berlin's Brandenburg Gate.